Abstract Background Pathological complete response (pCR) is a well-established prognostic factor in breast cancer WOVEN BASKET treated with neoadjuvant systemic therapy (naST).The determining factors of pCR are known to be intrinsic subtype, proliferation index, grading, clinical tumor and nodal stage as well as type of systemic therapy.The additio
IMPLEMENTASI TEORI KOMUNIKASI SOSIAL BUDAYA DALAM PEMBANGUNAN INTEGRASI BANGSA
Abstract Bar Refrigerators Development is a process that is carried out continuously in a region over time.Development leads the improvement of the lives and well-being, both in terms of material and nonmaterial.To Indonesia, the development process is a planned activity to achieve national goals as mandated in the 1945 Constitution, which among ot
The impact of currency clause and exchange rate on Serbian economy
In nineties Serbia survived the disintegration of the former Yugoslavia, intense UN sanctions, and 1999 78 days of bombing by NATO.This has resulted in a drop in production Salt Lamps and hyperinflation.The confidence in the national currency the dinar has been lost.In order to do business in Serbia returned to normal framework the Law on Foreign E
Genetic diversity and phylogeographic dynamics of avihepadnavirus: a comprehensive full-length genomic view
Avihepadnavirus is a genus of the Hepadnaviridae family.It primarily infects birds, including species of duck, geese, cranes, storks, and herons etc.To understand the genetic relatedness and evolutionary diversity among avihepadnavirus strains, a comprehensive analysis of the available 136 full-length viral genomes (n = 136) was conducted.The genom
Deazaneplanocin a is a promising drug to kill multiple myeloma cells in their niche.
Tumoral plasma cells has retained stemness features and in particular, a polycomb-silenced gene expression signature.Therefore, epigenetic therapy could be a mean to fight for multiple myeloma (MM), still an incurable pathology.Deazaneplanocin A (DZNep), a S-adenosyl-L-homocysteine hydrolase inhibitor, targets enhancer of zest homolog 2 (EZH2), a c